产品参数
Preci? human(人) VCAN (基因ID:1462) qPCR引物对 (全名:versican;别名:WGN,ERVR,GHAP,PG-M,WGN1,CSPG2)(tnt5158a) Preci? human(人) THBD (基因ID:7056) qPCR引物对 (全名:thrombomodulin;别名:TM,THRM,AHUS6,BDCA3,CD141,BDCA-3,THPH12)(tnt4269b) Preci? human(人) SFTPD (基因ID:6441) qPCR引物对 (全名:surfactant protein D;别名:SP-D,PSP-D,SFTP4,COLEC7)(tnt10104a) Preci? human(人) SFTPA2 (基因ID:729238) qPCR引物对 (全名:surfactant protein A2;别名:ILD2,PSAP,PSPA,SP-A,SPA2,PSP-A,SFTP1,SP-2A,SPAII,COLEC5,SFTPA2B) Preci? human(人) SFTPA1 (基因ID:653509) qPCR引物对 (全名:surfactant protein A1;别名:SPA,ILD1,PSAP,PSPA,SP-A,SPA1,PSP-A,SFTP1,SP-A1,COLEC4,SFTPA1B,SP-A1 beta,SP-A1 delta,SP-A1 gamma,SP-A1 epsilon) Preci? human(人) SELP (基因ID:6403) qPCR引物对 (全名:selectin P;别名:CD62,GRMP,PSEL,CD62P,GMP140,LECAM3,PADGEM)(tnt4010c) Preci? human(人) SELL (基因ID:6402) qPCR引物对 (全名:selectin L;别名:TQ1,LAM1,LEU8,LNHR,LSEL,CD62L,LYAM1,PLNHR,LECAM1)(tnt6411b) Preci? human(人) SELE (基因ID:6401) qPCR引物对 (全名:selectin E;别名:ELAM,ESEL,CD62E,ELAM1,LECAM2,selectin-e)(tnt4667b) Preci? human(人) PKD1 (基因ID:5310) qPCR引物对 (全名:polycystin 1, transient receptor potential channel interacting;别名:PBP,PC1,Pc-1,TRPP1) Preci? human(人) OLR1 (基因ID:4973) qPCR引物对 (全名:oxidized low density lipoprotein receptor 1;别名:LOX1,LOXIN,SLOX1,CLEC8A,SCARE1)(tnt3859a) Preci? human(人) NCAN (基因ID:1463) qPCR引物对 (全名:neurocan;别名:CSPG3) Preci? human(人) MRC2 (基因ID:9902) qPCR引物对 (全名:mannose receptor C-type 2;别名:CD280,UPARAP,CLEC13E,ENDO180) Preci? human(人) MRC1 (基因ID:4360) qPCR引物对 (全名:mannose receptor C-type 1;别名:MMR,hMR,CD206,MRC1L1,CLEC13D,CLEC13DL,bA541I19.1)(tnt1138b) Preci? human(人) LY75 (基因ID:4065) qPCR引物对 (全名:lymphocyte antigen 75;别名:CD205,LY-75,CLEC13B,DEC-205,GP200-MR6) Preci? human(人) KLRK1 (基因ID:22914) qPCR引物对 (全名:killer cell lectin like receptor K1;别名:KLR,CD314,NKG2D,NKG2-D,D12S2489E)(tnt7297b) Preci? human(人) KLRG2 (基因ID:346689) qPCR引物对 (全名:killer cell lectin like receptor G2;别名:CLEC15B) Preci? human(人) KLRG1 (基因ID:10219) qPCR引物对 (全名:killer cell lectin like receptor G1;别名:2F1,MAFA,MAFA-L,CLEC15A,MAFA-2F1,MAFA-LIKE)(tnt8050b) Preci? human(人) KLRF2 (基因ID:100431172) qPCR引物对 (全名:killer cell lectin like receptor F2;别名:NKp65) Preci? human(人) KLRF1 (基因ID:51348) qPCR引物对 (全名:killer cell lectin like receptor F1;别名:NKp80,CLEC5C) Preci? human(人) KLRD1 (基因ID:3824) qPCR引物对 (全名:killer cell lectin like receptor D1;别名:CD94) Preci? human(人) KLRC3 (基因ID:3823) qPCR引物对 (全名:killer cell lectin like receptor C3;别名:NKG2E,NKG2-E) Preci? human(人) KLRC2 (基因ID:3822) qPCR引物对 (全名:killer cell lectin like receptor C2;别名:NKG2C,CD159c,NKG2-C) Preci? human(人) KLRC1 (基因ID:3821) qPCR引物对 (全名:killer cell lectin like receptor C1;别名:NKG2,NKG2A,CD159A)(tnt7296a) Preci? human(人) KLRB1 (基因ID:3820) qPCR引物对 (全名:killer cell lectin like receptor B1;别名:NKR,CD161,CLEC5B,NKR-P1,NKRP1A,NKR-P1A,hNKR-P1A) Preci? human(人) FCER2 (基因ID:2208) qPCR引物对 (全名:Fc epsilon receptor II;别名:CD23,FCE2,CD23A,IGEBF,CLEC4J,FCErII,BLAST-2)(tnt3816c1) Preci? human(人) COLEC12 (基因ID:81035) qPCR引物对 (全名:collectin subfamily member 12;别名:CLP1,NSR2,SRCL,SCARA4) Preci? human(人) COLEC11 (基因ID:78989) qPCR引物对 (全名:collectin subfamily member 11;别名:3MC2,CLK1,CL-11,CL-K1-I,CL-K1-II,CL-K1-IIa,CL-K1-IIb) Preci? human(人) COLEC10 (基因ID:10584) qPCR引物对 (全名:collectin subfamily member 10;别名:3MC3,CLL1,CL-10,CL-34) Preci? human(人) CLEC18C (基因ID:283971) qPCR引物对 (全名:C-type lectin domain family 18 member C;别名:MRCL,MRCL3) Preci? human(人) CLEC18B (基因ID:497190) qPCR引物对 (全名:C-type lectin domain family 18 member B;别名:MRCL2) Preci? human(人) CLEC18A (基因ID:348174) qPCR引物对 (全名:C-type lectin domain family 18 member A;别名:MRCL,MRCL1,MRLP2) Preci? human(人) CLEC12A (基因ID:160364) qPCR引物对 (全名:C-type lectin domain family 12 member A;别名:CLL1,MICL,CD371,CLL-1,DCAL-2) Preci? human(人) CLEC10A (基因ID:10462) qPCR引物对 (全名:C-type lectin domain containing 10A;别名:HML,MGL,HML2,CD301,CLECSF13,CLECSF14) Preci? human(人) CLEC9A (基因ID:283420) qPCR引物对 (全名:C-type lectin domain containing 9A;别名:CD370,DNGR1,DNGR-1,UNQ9341) Preci? human(人) CLEC7A (基因ID:64581) qPCR引物对 (全名:C-type lectin domain containing 7A;别名:BGR,CD369,CANDF4,SCARE2,DECTIN1,CLECSF12)(tnt5765a) Preci? human(人) CLEC4D (基因ID:338339) qPCR引物对 (全名:C-type lectin domain family 4 member D;别名:MCL,MPCL,CD368,CLEC6,CLEC-6,CLECSF8,Dectin-3) Preci? human(人) CLEC4C (基因ID:170482) qPCR引物对 (全名:C-type lectin domain family 4 member C;别名:DLEC,HECL,BDCA2,CD303,BDCA-2,CLECSF7,CLECSF11,PRO34150) Preci? human(人) CLEC4A (基因ID:50856) qPCR引物对 (全名:C-type lectin domain family 4 member A;别名:DCIR,LLIR,CD367,DDB27,hDCIR,CLECSF6,HDCGC13P) Preci? human(人) CD302 (基因ID:9936) qPCR引物对 (全名:CD302 molecule;别名:DCL1,DCL-1,BIMLEC,CLEC13A) Preci? human(人) CD248 (基因ID:57124) qPCR引物对 (全名:CD248 molecule;别名:TEM1,CD164L1) Preci? human(人) CD209 (基因ID:30835) qPCR引物对 (全名:CD209 molecule;别名:CDSIGN,CLEC4L,DC-SIGN,DC-SIGN1,hDC-SIGN)(tnt5837b) Preci? human(人) CD207 (基因ID:50489) qPCR引物对 (全名:CD207 molecule;别名:CLEC4K) Preci? human(人) CD93 (基因ID:22918) qPCR引物对 (全名:CD93 molecule;别名:C1QR1,C1qRP,CDw93,ECSM3,MXRA4,C1qR(P),dJ737E23.1)(tnt5764b) Preci? human(人) CD72 (基因ID:971) qPCR引物对 (全名:CD72 molecule;别名:LYB2,CD72b) Preci? human(人) CD69 (基因ID:969) qPCR引物对 (全名:CD69 molecule;别名:AIM,EA1,MLR-3,CLEC2C,GP32/28,BL-AC/P26)(tnt8062b) Preci? human(人) BCAN (基因ID:63827) qPCR引物对 (全名:brevican;别名:BEHAB,CSPG7) Preci? human(人) ACAN (基因ID:176) qPCR引物对 (全名:aggrecan;别名:AGC1,SEDK,AGCAN,CSPG1,MSK16,CSPGCP,SSOAOD)(tnt6015a) Preci? human(人) REG4 (基因ID:83998) qPCR引物对 (全名:regenerating family member 4;别名:GISP,RELP,REG-IV) Preci? human(人) REG3G (基因ID:130120) qPCR引物对 (全名:regenerating family member 3 gamma;别名:PAP1B,PAPIB,PAP IB,PAP-1B,UNQ429,LPPM429,REG III,REG-III) Preci? human(人) REG3A (基因ID:5068) qPCR引物对 (全名:regenerating family member 3 alpha;别名:HIP,PAP,PAP1,REG3,INGAP,PAP-H,PBCGF,HIP/PAP,REG-III) Preci? human(人) REG1B (基因ID:5968) qPCR引物对 (全名:regenerating family member 1 beta;别名:REGH,REGL,PSPS2,REGI-BETA) Preci? human(人) REG1A (基因ID:5967) qPCR引物对 (全名:regenerating family member 1 alpha;别名:P19,PSP,PTP,REG,ICRF,PSPS,PSPS1) Preci? human(人) PRG3 (基因ID:10394) qPCR引物对 (全名:proteoglycan 3, pro eosinophil major basic protein 2;别名:MBP2,MBPH) Preci? human(人) PRG2 (基因ID:5553) qPCR引物对 (全名:proteoglycan 2, pro eosinophil major basic protein;别名:MBP,BMPG,MBP1,proMBP)(tnt5676b) Preci? human(人) PLA2R1 (基因ID:22925) qPCR引物对 (全名:phospholipase A2 receptor 1;别名:PLA2R,PLA2-R,PLA2IR,CLEC13C,PLA2G1R) Preci? human(人) PKD1L3 (基因ID:342372) qPCR引物对 (全名:polycystin 1 like 3, transient receptor potential channel interacting;别名:) Preci? human(人) PKD1L2 (基因ID:114780) qPCR引物对 (全名:polycystin 1 like 2 (gene/pseudogene);别名:PC1L2) Preci? human(人) LAYN (基因ID:143903) qPCR引物对 (全名:layilin;别名:) Preci? human(人) FREM1 (基因ID:158326) qPCR引物对 (全名:FRAS1 related extracellular matrix 1;别名:BNAR,MOTA,TILRR,TRIGNO2,C9orf143,C9orf145,C9orf154) Preci? human(人) DGCR2 (基因ID:9993) qPCR引物对 (全名:DiGeorge syndrome critical region gene 2;别名:IDD,LAN,DGS-C,SEZ-12) Preci? human(人) CLEC20A (基因ID:400797) qPCR引物对 (全名:C-type lectin domain containing 20A;别名:LINC00083,NCRNA00083) Preci? human(人) CLEC19A (基因ID:728276) qPCR引物对 (全名:C-type lectin domain containing 19A;别名:) Preci? human(人) CLEC17A (基因ID:388512) qPCR引物对 (全名:C-type lectin domain containing 17A;别名:) Preci? human(人) CLEC16A (基因ID:23274) qPCR引物对 (全名:C-type lectin domain containing 16A;别名:Gop-1,KIAA0350) Preci? human(人) CLEC14A (基因ID:161198) qPCR引物对 (全名:C-type lectin domain containing 14A;别名:CEG1,EGFR-5,C14orf27)(tnt7179a) Preci? human(人) CLEC12B (基因ID:387837) qPCR引物对 (全名:C-type lectin domain family 12 member B;别名:UNQ5782) Preci? human(人) CLEC11A (基因ID:6320) qPCR引物对 (全名:C-type lectin domain containing 11A;别名:P47,SCGF,LSLCL,CLECSF3) Preci? human(人) CLEC6A (基因ID:93978) qPCR引物对 (全名:C-type lectin domain containing 6A;别名:CLEC4N,CLECSF10,dectin-2,hDECTIN-2)(tnt5766a) Preci? human(人) CLEC5A (基因ID:23601) qPCR引物对 (全名:C-type lectin domain containing 5A;别名:MDL1,MDL-1,CLECSF5) Preci? human(人) CLEC4G (基因ID:339390) qPCR引物对 (全名:C-type lectin domain family 4 member G;别名:LP2698,UNQ431,DTTR431,LSECtin) Preci? human(人) CLEC4F (基因ID:165530) qPCR引物对 (全名:C-type lectin domain family 4 member F;别名:KCR,KCLR,CLECSF13) Preci? human(人) CLEC4E (基因ID:26253) qPCR引物对 (全名:C-type lectin domain family 4 member E;别名:MINCLE,CLECSF9) Preci? human(人) CLEC3B (基因ID:7123) qPCR引物对 (全名:C-type lectin domain family 3 member B;别名:TN,TNA,MCDR4)(tnt6432b) Preci? human(人) CLEC3A (基因ID:10143) qPCR引物对 (全名:C-type lectin domain family 3 member A;别名:CLECSF1) Preci? human(人) CLEC2L (基因ID:154790) qPCR引物对 (全名:C-type lectin domain family 2 member L;别名:) Preci? human(人) CLEC2D (基因ID:29121) qPCR引物对 (全名:C-type lectin domain family 2 member D;别名:CLAX,LLT1,OCIL)(tnt4232b) Preci? human(人) CLEC2B (基因ID:9976) qPCR引物对 (全名:C-type lectin domain family 2 member B;别名:AICL,IFNRG1,CLECSF2,HP10085)(tnt3185a) Preci? human(人) CLEC2A (基因ID:387836) qPCR引物对 (全名:C-type lectin domain family 2 member A;别名:KACL,PILAR,UNQ5792,INPE5792) Preci? human(人) CLEC1B (基因ID:51266) qPCR引物对 (全名:C-type lectin domain family 1 member B;别名:CLEC2,CLEC2B,PRO1384,QDED721,1810061I13Rik) Preci? human(人) CLEC1A (基因ID:51267) qPCR引物对 (全名:C-type lectin domain family 1 member A;别名:CLEC1,CLEC-1) Preci? human(人) CHODL (基因ID:140578) qPCR引物对 (全名:chondrolectin;别名:MT75,PRED12,C21orf68) Preci? human(人) ATRNL1 (基因ID:26033) qPCR引物对 (全名:attractin like 1;别名:ALP,bA338L11.1,bA454H24.1) Preci? human(人) ATRN (基因ID:8455) qPCR引物对 (全名:attractin;别名:MGCA,DPPT-L) Preci? human(人) ASGR2 (基因ID:433) qPCR引物对 (全名:asialoglycoprotein receptor 2;别名:HL-2,HBXBP,ASGPR2,ASGP-R2,CLEC4H2) Preci? human(人) ASGR1 (基因ID:432) qPCR引物对 (全名:asialoglycoprotein receptor 1;别名:HL-1,ASGPR,ASGPR1,CLEC4H1)
“含有C型凝集素结构域”的基因群主要涵盖了编码具有C型凝集素结构域蛋白的基因。这些基因在生物学上扮演着重要的角色,特别是在免疫系统中作为模式识别受体发挥作用。以下是对这一基因群的详细解析:
C型凝集素的结构与功能:
C型凝集素是一类含有钙离子(Ca2+)依赖糖识别域(CRD)的蛋白超家族,它们通过其特定的结构域与糖类物质结合。
这类蛋白在固有免疫系统中作为重要的模式识别受体(PRR),能够识别并结合病原体表面的特定糖类结构,从而触发免疫反应。
基因群的特点:
编码的蛋白质具有C型凝集素结构域,该结构域赋予了它们与糖类物质结合的能力。
这类基因在基因组中的分布广泛,可以在多个染色体上找到它们的存在。
不同的C型凝集素蛋白可能具有不同的糖识别特异性和生物学功能。
具体基因实例:
CLEC7A(C-type lectin domain family 7, member A):位于12号染色体,编码的蛋白Dectin-1是一种模式识别受体,可以识别真菌和植物的多种β-葡聚糖,在先天免疫应答中发挥作用。
CLEC2C(CD69):是一种II型跨膜糖蛋白,属于C型凝集素受体家族,是NK细胞信号转导基因复合体家族的一员,参与T淋巴细胞的活化和增殖。
CLEC16A:编码的蛋白属于C型凝集素家族,与糖尿病、多发性硬化症和类风湿性关节炎等疾病有关。
基因群的功能与分类:
功能上,这些基因编码的蛋白主要参与免疫反应和细胞识别过程,通过识别病原体表面的糖类结构触发免疫反应。
分类上,C型凝集素可以根据其亚细胞定位分为可溶型和膜型两类。可溶型C型凝集素包括lectican、collectins等,而膜型C型凝集素则主要位于细胞表面,如CLEC7A和CLEC2C。
研究意义:
对“含有C型凝集素结构域”基因群的研究有助于我们更深入地了解C型凝集素在免疫系统中的作用机制,以及它们在疾病发生和发展中的作用。
这为开发新的药物和治疗方法提供了新的思路,特别是在针对病原体感染和免疫相关疾病的治疗中。